|
Research project |
Institution on whose behalf the research is
being undertaken |
Researcher |
Description |
Acute Pain Service
|
|
Comparison between the effectiveness of commencing epidural
infusion analgesia intra-operatively to commencing the infusion
postoperatively. |
Acute Pain Service, Port Kembla Hospital. |
Negus B,
Brown D, Markocic S. |
Two recurrent problems with post-operative epidural infusions
are inadequate analgesia and hypotension. Concerns with
increased patient discomfort and prolonged recovery ward stays
instigated this study into the benefit of earlier commencement of
the epidural infusion, ie during surgery in comparison to
commencement in the recovery ward. |
|
Comparison between morphine and morphine and ketamine for
total
knee replacements. |
Acute Pain Service, Port Kembla Hospital, |
Jeffs
C,
Markocic S. |
The study investigates the post operative total knee replacement
pain management benefits of administering Ketamine in addition
to Morphine. |
|
Double-blind, double-dummy, randomised, parallel-arm equivalence
(non-inferiority) study comparing hydromorphone hydrochloride
extended-release capsules to MS Contin tablets, dosed at a ratio
of 1:7.5, in cancer or non-cancer patients with a history of
moderate to severe pain. |
Chronic Pain Service, Port Kembla Hospital. |
Bashford G. |
The purpose of this research is to compare the safety and
effectiveness of a long-acting (extended-release) hydromorphone
to long-acting morphine in patients with long-standing moderate
to severe cancer or non-cancer pain. |
|
A
double-blind, randomised, parallel group study to compare the
efficacy, safety, and tolerability of OxyContin taken in
combination with Gabapentin, versus placebo with Gabapentin, for
the treatment of moderate to severe neuropathic pain in patients
with diabetes mellitus. |
Chronic Pain Service, Port Kembla Hospital. |
Bashford G. |
Selected patients have experienced moderate to severe
neuropathic pain due to diabetic peripheral neuropathy. The
study aims to identify whether OxyContin, when taken in addition
to Gabapentin, is a useful treatment for neuropathic pain. |
Medical Stream
|
|
A
phase III, parallel, double-blind, multi-centre trial to examine
inducible myocardial perfusion abnormality detection with
BMS068645 and Adenosine stress single photon emission computed
tomography (SPECT) compared to coronary angiography. |
Bristol-Myers Squibb. |
Elison B,
Harvey S. |
Investigating whether the study drug (BMS068645) has the
potential to dilate coronary arteries prior to the
administration
of a radioisotope for cardiac imaging, without
unwanted side effects. |
|
A
comparison of bioelectrical impedance with dual energy x-ray
absorptiometry for the determination of body fat in overweight
and obese children aged 5-9 years. |
Nutrition Department, The Wollongong Hospital. |
Nowland A,
Cleary J.
|
This study aims to compare assessments of percentage body fat
obtained using a field method, bioelectrical impedance
assessment (BIA) to the reference method, dual energy
x-ray absorptiometry in children. It is a sub study to the project: “The efficacy of a physical
activity skill-development program and parent-centred dietary
modification program for overweight and obese children”.
The results
of this sub study will then be used to validate the
data collected using the BIA on changes
in body fat of children
that have participated
in this intervention study.
|
|
Ventilation perfusion SPECT: should ventilation perfusion
imaging be routinely performed using SPECT? |
University of Newcastle. |
Fenwick J. |
The aim of this study is to determine if ventilation perfusion
imaging should be routinely performed using single photon
emission computed tomography (SPECT) in
the diagnosis of
pulmonary embolism.
|
|
Accuracy and prognostic value of myocardial perfusion
scintigraphy when compared to coronary angiography and clinical
outcome. |
Department of Nuclear Medicine, Nepean Hospital. |
Chan WL. |
The project is evaluating the diagnostic accuracy of myocardial
perfusion imaging
(for detection / assessment of coronary artery disease) by
comparison with the gold standard coronary angiography, and to
assess its prognostic value by correlation with clinical
outcomes. The project has potential significance in that the results may permit more appropriate and selective
use of myocardial perfusion imaging in the future.
|
|
Evaluation of immediate post stress (exercise or
pharmacological) gated single photon
emission computed tomography (SPECT) compared to standard post stress
gated stress imaging in myocardial perfusion imaging. |
Department of Nuclear Medicine, Wollongong Hospital. |
Elison B,
Arvela O,
Chan WL,
Shen L,
Harvey S.
|
Conventional gated SPECT cardiac imaging
for evaluation of left
ventricular wall motion and left ventricular wall thickening
(function)
is routinely performed at approximately 30 minutes
after injection of the radioisotope,
as part of myocardial
perfusion scanning for detection / assessment of coronary artery
disease. Conventional gated SPECT studies evaluate left
ventricular function and wall motion in a more ‘resting’ state
rather than
a true post stress (exercise) state.
Evaluating a true stress (exercise) gated SPECT study
will improve the specificity of this investigation,
notwithstanding the fact that there are well published
sensitivity / specificity data regarding myocardial perfusion
scanning utilising the conventional gated SPECT studies, and the myocardial perfusion scanning
should identify ischaemia in a direct sense (abnormal
wall motion post exercise) and an indirect sense by evaluating
areas of ischaemia in the myocardium, thereby markedly improving
sensitivity and specificity.
|
|
Clarity Timi 28. |
Bristol Myers Squibb. |
Owensby D, NguyenDang T, McKenzie W.
|
Comparing Clopidogrel versus placebo in the setting of standard
treatment for myocardial infarction on culprit artery patency. |
|
HAT Study. |
National Institute Health, USA. |
Owensby D,
Ryan M,
Vogl E.
|
Evaluating the use of automatic portable defibrillators in the
home of patients with anterior myocardial infarction. |
|
Illuminate study. |
Pfizer. |
Owensby D,
Vogl E,
Nguyen Dang T, Dunn C,
Ford C,
Twomey P.
|
Comparing Lipitor to Lipitor plus. A new drug agent that raises HDL
on cardiovascular outcomes in high risk patients. |
|
Ontarget. |
Boehringer Ingelheim. |
Owensby D. |
Comparing Ramipril with Terlmisartan on cardiovascular outcomes
in patients with high risk cardiovascular disease. |
|
Oasis 5. |
Sanofi Synthelabo. |
Owensby D. |
Comparing Fondaparinux with the standard treatment Enoxaparin in
acute coronary syndrome stabilisation. |
|
IDEAL. |
Collaborative study with Australian and New Zealand renal
physicians. |
Lonergan M. |
Comparing the initiation
of dialysis, early and late. |
|
ESP. |
Multinational and multicompany study. |
Lonergan M. |
To
determine whether treating cholesterol in chronic renal failure
and end stage renal failure is beneficial. |
|
Renal Robics. |
Wollongong and Shoalhaven Hospitals' Renal Units; University of Wollongong. |
Lonergan M. |
To
determine whether an organised exercise program improves
outcomes in patients receiving haemodialysis. |
|
FTY 720AZ218 study. |
Novartaris. |
Lonergan M. |
Evaluating the safety of drugs and steroids in adult renal transplant
recipients. |
|
HE05/093 renal impairment. |
University of Wollongong. |
Lonergan M. |
Management of patients with diabetes prior to commencing dialysis. |
|
Sirolimus 310 AU. |
WYETH. |
Lonergan M. |
Multinational study comparing different drug therapies in renal transplant.
|
|
Survey of elderly persons and their health priorities regarding
need for colonoscopy. |
Department of Gastroenterology, Wollongong Hospital. |
Ayonrinde K, McDonald J.
|
A
survey of elderly people to ascertain their priorities regarding
their health and their views regarding screening colonoscopies. |
|
Indications and appropriateness of patients referred for
percutaneous endoscopic gastrostomy (PEG) tube insertion. |
Department of Gastroenterology, Wollongong Hospital. |
Ayonrinde K, McDonald J. |
A survey of the indications and appropriateness of inserting PEG
tubes
and the outcomes after 30 days. |
|
Upper gastrointestinal bleeding and relationship of
anti-coagulant / anti-platelet medication. |
Department of Gastroenterology, Wollongong Hospital. |
Ayonrinde K, McDonald J. |
A
survey to ascertain any relationship between upper
gastrointestinal bleeding
and the use of anti-coagulant and / or anti-platelet drugs. |
|
Outcomes and complications related to capsule endoscopy. |
Department of Gastroenterology, Wollongong Hospital. |
Abey S. |
An
ongoing survey on the outcomes and complications of patients
undergoing capsule endoscopy. |
Critical Care
|
|
Severe Sepsis (XIGRIS).
|
Eli Lilly Australia Pty Ltd. |
Simmons G. |
A
trial of prophylactic (prevention) heparin in patients with severe sepsis and higher
disease severity who are undergoing treatment with Drotrecogin
Alfa (activated). |
|
Normoglycaemia (NICE).
|
The George Institute for International Health. |
Rachakonda
S. |
A
multi-centre trial examining two target ranges for glycaemic control in
patients in intensive care. |
|
Hospital Acquired Pneumonia (ATTAIN).
|
Omnicare Clinical Research. |
Simmons G. |
A
multinational
trial of intravenous Telavancin versus Vancomycin for treatment
of hospital acquired pneumonia, with a focus on patients with
infections due to methicillin-resistant staphylococcus aureus (MRSA). |
Nutrition
|
|
Review of dietary management of ulcerative colitis. |
Nutrition Department, Wollongong Hospital. |
Haantjens A. |
Reviewing
current practices at Wollongong Hospital with the aim of
ensuring that the
approach taken is consistent across clinicians, and follows best
practice guidelines. |
|
Review of the dietary management of Chrons Disease. |
Nutrition Department, Wollongong Hospital. |
Haantjens A. |
Reviewing
current practices at Wollongong Hospital with the aim of
ensuring that the approach taken is consistent across clinicians,
and follows best practice guidelines. |
|
Dual energy x-ray
bsorptiometry (DXA) versus
bioelectrical impedance assessment (BIA). Which one is the best tool to use in children when
estimating body composition? |
Nutrition Department, Wollongong Hospital. |
Cleary J,
Nowland A. |
Comparing tools
used to measure the body composition of children. |
|
A
review of best practice guideless in inflammatory bowel diseases. |
Nutrition Department, Wollongong Hospital. |
Lambert K. |
This project reviews current literature in this area
and also benchmarks our practice with other hospitals throughout
Australia. The main aim is to ensure we are meeting the best
practice guidelines in this area. |
|
Do patients with communication difficulties having greater
difficulty accessing choice on the menu? |
Nutrition Department, Wollongong Hospital. |
Milosavljevic M. |
This projects specifically examines patients with
communications difficulties ie non-English speaking, verbal difficulties,
dementia, and what issues they experience with their meals. It
utilises speech therapy techniques for the non-verbal patients
and uses interpreters when required. It is the first menu
survey that includes this category of patients. |
|
The effects of transfer from a
palliative care unit to a nursing home on patients and their
carers |
Illawarra Community Health. |
Garrard J. |
Qualitative study interviewing patients
and carers who have been transferred from a palliative care unit
to a nursing home, and asking about their experience of the
process
of transfer. |
|
Randomised, parallel-arm equivalence
study comparing Hydromorphone Hydrochloride extended-release (HHER)
capsules with Ms Contin tablets, at a dose ratio of 1:7.5, in
cancer or non-cancer patients with a history of moderate to
severe pain. |
Mundipharma Pty Ltd. |
Davis JM. |
An equivalence clinical trial for
people with moderate to severe pain (cancer or non-cancer)
comparing HHER and MS Contin. Patients whose pain is stabilised
for 48 hours are randomised to either drug for two weeks. |
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