South Eastern Sydney and Illawarra Area Health Service
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Research Activity 2004/05

Research project Institution on whose behalf the research is being undertaken Researcher Description
Double-blind, double-dummy, randomised, parallel-arm equivalence study comparing hydromorphone hydrochloride extended-release capsules with MS Contin tablets, at a dose ratio of 1:7.5, in cancer or non-cancer patients with a history of moderate to severe pain. Mundipharma Pty Ltd. Davis JM. Comparing treatment therapies for people with or without cancer with moderate to severe pain.
The effects of transfer from a palliative care unit to a nursing home, on patients and their carers. Calvary Health Care Sydney. Garrard J. Determining patients and carers experience of the process of transfer  from a palliative care unit to a nursing home.
A double-blind, placebo-controlled, trial of Zoloft’s effects on symptoms and survival time in advanced cancer (ZEST). NHMRC Clinical Trial Centre; NSW Co-operative Oncology Group. Gorman D. This trial looks at the benefits of using a mild anti-depressant in patients who are not clinically depressed.
Open-label, Phase ll trial to assess symptom control, weight change and the tolerability of Olanzapine in cancer patients with anorexia-cachexia syndrome. Calvary Health Care Sydney. Davis JM. Patients with cancer who have rapid weight loss leading to anorexia-cachexia are using Olanzapine for 12 weeks and the effect on weight, appetite and quality of life measured.
The subjective experience of Asian women from a non-English speaking background in caring for a dying relative at home. Calvary Health Care Sydney. Heidenric M. Based on evidence demonstrating a disparity in service provision for Asian women caring for a dying relative at home, this research project identifies the specific needs of this group.
A double-blind, randomised, parallel group study to compare the efficiacy, safety and tolerability of OxyContin taken in combination with Gabapentin versus placebo with Gabapentin, for the treatment of moderate to severe neuropathic pain in patients with diabetes mellitus. Mundipharma Pty Ltd. Gorma D. To evaluate which analgesia is superior and to compare the two treatments with respect to sleep quality.
Investigating the prevalence of white matter hyperintensities found on magnetic resonance imaging (MRI) in older patients with falls resulting in a fractures neck of femur requiring surgery, compared to the MRI of older patients presenting for hip replacement surgery. Calvary Health Care Sydney. Schwarz R. The aim of this pilot study is to identify whether patients with falls resulting in a fractured neck of femur have increased white matter hyperintensities on MRI findings, compared to those who undergo elective hip replacement surgery.
Ageing well for the over 45s. Calvary Health Care Sydney. Sheriff J. A project designed to enhance participant’s awareness of their health status, improve their knowledge of factors contributing to good health and provide them with an opportunity to develop skills in assessing, monitoring and managing their health.
Keeping well in chronic illness. Calvary Health Care Sydney. Donoghue J. To investigate self-care behaviours and related self-efficacy, sense of coherence, social support and illness severity in four populations of older people with chronic illness, as a basis for developing nursing interventions that help patients attain and maintain optimal self-care behaviours.
An investigation of service needs of bereaved carers after a Calvary Health Care Sydney-related death. Calvary Health Care Sydney; SESIAHS Carers Program. Connell S. This project seeks to determine the needs of bereaved carers, with a view to improving and expanding services for bereaved carers. 
A cross study on the relationship between biguanides, proton pump inhibitors (PPI) and malnutrition, and serum vitamin B12 levels in an elderly populations. Calvary Health Care Sydney. O’Leary F. A research project designed to look at nutrient intake and nutritional status in an elderly population, and determine if there is an association between sub-optimal levels of vitamin B12 and malnutrition, biguanides for the treatment of diabetes and the consumption of commonly prescribed PPIs for the treatment of gastric reflux disease.
Better defining neuropathic pain: a double-blind, randomised trial of signs and symptoms in sciatic pain before and after Gabapentin therapy. Calvary Health Care Sydney. Gorman D. A study of the symptoms and signs in sciatic pain before and after Gabapentin to better define neuropathic pain.
Signs and symptoms in neuropathic pain in spinal metastases before and after radiotherapy. Calvary Health Care Sydney. Gorman D. A study of signs and symptoms before and after radiotherapy to better define which pains are neuropathic.
A multi-centre, randomised, double-blind, controlled trial of oxygen versus air for the relief of breathlessness in terminally-ill patients with intractable dyspnoea and PaO2 > 55mmHg. Repatriation General Hospital, SA; Flinders University. Davis JM. This trial seeks to establish the role of oxygen in the context of providing relief of the sensation of breathlessness for terminally ill patients.